Effect of p16 positivity in oral cavity and oropharyngeal squamous cell carcinoma
نویسندگان
چکیده
منابع مشابه
Prognostic factors in oral cavity and oropharyngeal squamous cell carcinoma.
BACKGROUND The survival of patients with head and neck squamous cell carcinoma (HNSCC) remains unaffected despite recent therapeutic advances. To reverse this trend, reliable and clinically applicable markers of tumor aggressiveness must be identified. One such marker may be the tumor-associated macrophage content. The authors hypothesized that tumor-associated macrophages contribute to HNSCC a...
متن کاملOral cavity and oropharyngeal squamous cell carcinoma--an update.
Oral cavity squamous cell carcinoma (OC-SCC) is the most common malignancy of the head and neck (excluding nonmelanoma skin cancer). Recent trends have shown a dramatic rise in the incidence of oropharyngeal squamous cell carcinoma (OP-SCC), with a marked increase in lesions related to human papillomavirus infection. This update presents the latest evidence regarding OC-SCC and OP-SCC. In parti...
متن کاملCorrelation of PET-CT nodal SUVmax with p16 positivity in oropharyngeal squamous cell carcinoma
BACKGROUND The incidence of human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) has been rising in recent years. Given the clinical impact of HPV/p16 positivity in OPSCC, identifying surrogate markers of this disease early in the diagnostic work-up of these patients could improve patient care. METHODS Demographic, pathologic, staging and PET-CT data from patients ...
متن کاملInduction Chemotherapy for p16 Positive Oropharyngeal Squamous Cell Carcinoma
OBJECTIVES/HYPOTHESIS We aimed to determine the effectiveness of induction chemotherapy for treating p16-positive oropharyngeal cancer in our department. STUDY DESIGN This was a retrospective case series to assess treatment effectiveness. METHODS We administered induction chemotherapy to patients with stage III to IV oropharyngeal p16-positive squamous cell carcinoma between 2008 and 2013. ...
متن کاملAsymptomatic p16-positive oropharyngeal squamous cell carcinoma: an emerging trend.
IMPORTANCE The rapid increase of human papillomavirus-associated oropharyngeal cancer has demonstrated a need for new strategies in prevention, diagnosis, evaluation, and treatment. Because there are currently no available screening technologies to detect early disease, a trend of purely incidentally identified asymptomatic p16-positive squamous cell carcinoma has been observed. We identify and...
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ژورنال
عنوان ژورنال: ENT Updates
سال: 2017
ISSN: 2149-7109,2149-6498
DOI: 10.2399/jmu.2017001009